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| Catalog Number | Size | Price |
|---|---|---|
| LS-C313102-10 | 10 µg | $318 |
| LS-C313102-100 | 100 µg | $470 |
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Polyclonal Rabbit anti‑Human NRG1 / Heregulin / Neuregulin Antibody (aa617‑636, IHC, WB) LS‑C313102
Polyclonal Rabbit anti‑Human NRG1 / Heregulin / Neuregulin Antibody (aa617‑636, IHC, WB) LS‑C313102
Note: This antibody replaces LS-C389001
Antibody:
NRG1 / Heregulin / Neuregulin Rabbit anti-Human Polyclonal (aa617-636) Antibody
Application:
IHC, IHC-P, IHC-Fr, ICC, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
NRG1 / Heregulin / Neuregulin Rabbit anti-Human Polyclonal (aa617-636) Antibody
Application:
IHC, IHC-P, IHC-Fr, ICC, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
Neuregulin antibody LS-C313102 is an unconjugated rabbit polyclonal antibody to Neuregulin (NRG1 / Heregulin) (aa617-636) from human. It is reactive with human, mouse and rat. Validated for ICC, IHC and WB.
Target
Human NRG1 / Heregulin / Neuregulin
Synonyms
NRG1 | ARIA | GGF | GGF2 | Glial growth factor | Heregulin | HRGA | MSTP131 | NDF | Neu differentiation factor | Neuregulin 1 type IV beta 3 | Neuregulin 1 type IV beta 1a | HRG1 | NRG-1 | SMDF | Neuregulin 1 | Pro-NRG1 | HGL | MST131
Host
Rabbit
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunogen affinity purified
Modifications
Unmodified
Immunogen
A synthetic peptide corresponding to a sequence at the C-Terminus of human NRG1(617-636 aa RFSTQEEIQARLSSVIANQD), different from the related rat and mouse sequences by one amino acids.
Epitope
aa617-636
Specificity
Type I isoforms are the predominant forms expressed in the endocardium. Isoform alpha is expressed in breast, ovary, testis, prostate, heart, skeletal muscle, lung, placenta liver, kidney, salivary gland, small intestine and brain, but not in uterus, stomach, pancreas, and spleen. Isoform 3 is the predominant form in mesenchymal cells and in non-neuronal organs, whereas isoform 6 is the major neuronal form. Isoform 8 is expressed in spinal cord and brain. Isoform 9 is the major form in skeletal muscle cells; in the nervous system it is expressed in spinal cord and brain. Also detected in adult heart, placenta, lung, liver, kidney, and pancreas. Isoform 10 is expressed in nervous system: spinal cord motor neurons, dorsal root ganglion neurons, and brain. Predominant isoform expressed in sensory and motor neurons. Not detected in adult heart, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Not expressed in fetal lung, liver and kidney. Type IV isoforms are brain-specific. .
Applications
- IHC
- IHC - Paraffin
- IHC - Frozen
- ICC
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg Thimerosal, 0.05mg sodium azide.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500µg/ml.
Storage
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About NRG1 / Heregulin / Neuregulin
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
Western blot
Species:
Human
Applications:
Western blot, ELISA
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/25/2024
Date Requested: 11/25/2024
