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| Catalog Number | Size | Price |
|---|---|---|
| LS-B1668-50 | 50 µg (0.5 mg/ml) | $460 |
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IHC‑plus™ Monoclonal Mouse anti‑Human NFKB1 / NF‑Kappa‑B Antibody (clone 4D1, IHC, IF, WB) LS‑B1668
IHC‑plus™ Monoclonal Mouse anti‑Human NFKB1 / NF‑Kappa‑B Antibody (clone 4D1, IHC, IF, WB) LS‑B1668
Note: This antibody replaces LS-C40935
Antibody:
NFKB1 / NF-Kappa-B Mouse anti-Human Monoclonal (4D1) Antibody
Application:
IHC, IHC-P, IF, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
NFKB1 / NF-Kappa-B Mouse anti-Human Monoclonal (4D1) Antibody
Application:
IHC, IHC-P, IF, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
NF-Kappa-B antibody LS-B1668 is an unconjugated mouse monoclonal antibody to human NF-Kappa-B (NFKB1). Validated for IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 4 publications.
Target
Human NFKB1 / NF-Kappa-B
Synonyms
NFKB1 | Ebp- 1 | EBP-1 | NF-KappaB p50 | NFkappaB | NFKB-p50 | KBF1 | NF-kappa-B | NF-kappaB | NF-kB1 | NFKB-p105 | p105 | p50 | DNA binding factor KBF1 | DNA-binding factor KBF1 | NF-kappabeta
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
4D1
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Recombinant human NFKB1.
Specificity
Recombinant full-length human NF-kB p50
Applications
- IHC
- IHC - Paraffin (15 µg/ml)
- Immunofluorescence
- Western blot
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B1668 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1668 was determined to be 15 ug/ml.
Presentation
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
Storage
Store at 4°C. Avoid freezing.
Restrictions
For research use only. Intended for use by laboratory professionals.
About NFKB1 / NF-Kappa-B
Validation
Anti-NFKB1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
Anti-NFKB1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ NFKB1 / NF-Kappa-B Antibody (clone 4D1) for IHC, IF/Immunofluorescence, WB/Western LS-B1668 has an LSBio Rating of
Publications (4.3)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (4)
Requirement for both JAK-mediated PI3K signaling and ACT1/TRAF6/TAK1-dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells. Huang F, Kao CY, Wachi S, Thai P, Ryu J, Wu R. Journal of immunology (Baltimore, Md. : 1950). 2007 179:6504-13.
Requirements for two proximal NF-kappaB binding sites and IkappaB-zeta in IL-17A-induced human beta-defensin 2 expression by conducting airway epithelium. Kao CY, Kim C, Huang F, Wu R. The Journal of biological chemistry. 2008 283:15309-18.
NF-B regulates MICA gene transcription in endothelial cell through a genetically inhibitable control site. Lin D, Lavender H, Soilleux EJ, O'Callaghan CA. The Journal of biological chemistry. 2012 287:4299-310.
1,25-dihydroxyvitamin D3 impairs NF- kappa B activation in human naïve B cells. Geldmeyer-Hilt K, Heine G, Hartmann B, Baumgrass R, Radbruch A, Worm M. Biochemical and biophysical research communications. 2011 Apr;407:699-702.
Customer Reviews (0)
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Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Reactivity:
Human
Range:
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
