Human Mucin 2 / MUC2

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1,k Monoclonal

CCP58

Unconjugated

Protein G purified

Azide-free, BSA-free. Also available Unmodified or Ready-to-Use.

Amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT, from human MUC2 / Mucin-2 protein, were used as the immunogen for this antibody. Percent identity by BLAST analysis: Human, Dog (86%); Chimpanzee (83%).

Human Mucin 2 / MUC2

• IHC
• IHC - Paraffin (0.5 - 1 µg/ml)
• Immunofluorescence (1 - 2 µg/ml)
• Western blot
• Immunoprecipitation
• Flow Cytometry (0.5 - 1 µg/10E6 cells)
• ELISA

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes a single glycoprotein of 520kDa, identified as MUC2 (Mucin-2). The MUC2 antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine and colon. in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary. ELISA: Order BSA-free antibody format for coating.

1X PBS

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q02817 NCBI: NM_002457 NP_002448.3