Target
Human MUC4
Synonyms
MUC4 | ASGP | HSA276359 | Mucin-4 | Testis mucin | Tracheobronchial mucin | Ascites sialoglycoprotein | MUC-4 | Mucin 4, tracheobronchial
Reactivity
Human, Rat
(tested or 100% immunogen sequence identity)
Purification
Immunogen affinity purified
Immunogen
E.coli-derived human MUC4 recombinant protein (Position: M1249-D1444). Human MUC4 shares 69% and 36% amino acid (aa) sequences identity with mouse and rat MUC4, respectively.
Specificity
Expressed in the thymus, thyroid, lung, trachea, esophagus, stomach, small intestine, colon, testis, prostate, ovary, uterus, placenta, and mammary and salivary glands. Expressed in carcinomas arising from some of these epithelia, such as lung cancers, squamous cell carcinomas of the upper aerodigestive tract, mammary carcinomas, biliary tract, colon, and cervix cancers. Minimally or not expressed in the normal pancreas or chronic pancreatitis, but is highly expressed in pancreatic tumors and pancreatic tumor cell lines. .