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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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MAPK10 / JNK3
mitogen-activated protein kinase 10
Serine/threonine-protein kinase involved in various processes such as neuronal proliferation, differentiation, migration and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK10/JNK3. In turn, MAPK10/JNK3 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. Plays regulatory roles in the signaling pathways during neuronal apoptosis. Phosphorylates the neuronal microtubule regulator STMN2. Acts in the regulation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP. Participates also in neurite growth in spiral ganglion neurons.
| Gene Name: | mitogen-activated protein kinase 10 |
| Family/Subfamily: | Protein Kinase , MAPK |
| Synonyms: | MAPK10, C-Jun N-terminal kinase 3, JNK3, JNK3A, MAPK 10, MAP kinase 10, MAP kinase p49 3F12, p493F12, p54B SAPK, SAPK beta, p54bSAPK, SAPK1b, Serk 2, JNK3 alpha protein kinase, PRKM10 |
| Target Sequences: | NM_002753 NP_002744.1 P53779 |
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MAPK10 / JNK3
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MAPK10 / JNK3 Rabbit anti-Human Polyclonal (aa342-391) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
MAPK10 / JNK3 Mouse anti-Human Monoclonal (10E4A4) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µl/$483
MAPK10 / JNK3 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
MAPK10 / JNK3 Rabbit anti-Human Polyclonal (p185) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
MAPK10 / JNK3 Rabbit anti-Human Polyclonal (330-410 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MAPK10 / JNK3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
MAPK10 / JNK3 Rabbit anti-Human Polyclonal (Lys391) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
MAPK10 / JNK3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, IP, WB
Unconjugated
30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351
MAPK10 / JNK3 Mouse anti-Human Monoclonal (Amino Acid: 28-233) (10E4A4) Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
100 µl/$541
MAPK10 / JNK3 Rabbit anti-Mouse Polyclonal (aa7-35) Antibody
Mouse
ELISA, IHC, WB
Unconjugated
200 µl/$734
MAPK10 / JNK3 Rabbit anti-Mouse Polyclonal (aa7-35) (Biotin) Antibody
Mouse
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
MAPK10 / JNK3 Rabbit anti-Mouse Polyclonal (aa7-35) (FITC) Antibody
Mouse
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
MAPK10 / JNK3 Rabbit anti-Mouse Polyclonal (aa7-35) (APC) Antibody
Mouse
ELISA, IHC, WB
APC Conjugated
200 µl/$952
MAPK10 / JNK3 Rabbit anti-Mouse Polyclonal (aa7-35) (Azide-free) (HRP) Antibody
Mouse
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
MAPK10 / JNK3 Rabbit anti-Mouse Polyclonal (aa7-35) (PE) Antibody
Mouse
ELISA, IHC, WB
PE Conjugated
200 µl/$952
MAPK10 / JNK3 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
MAPK10 / JNK3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
MAPK10 / JNK3 Mouse anti-Human Monoclonal (8A5D11) Antibody
Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$380
MAPK10 / JNK3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$341
MAPK10 / JNK3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
MAPK10 / JNK3 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
MAPK10 / JNK3 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
MAPK10 / JNK3 Rabbit anti-Human Polyclonal (p185) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
MAPK10 / JNK3 Rabbit anti-Human Polyclonal (pTyr185) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
MAPK10 / JNK3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25
of 66
product results
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