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| Catalog Number | Size | Price |
|---|---|---|
| LS-C391567-100 | 100 µg (1 mg/ml) | $574 |
Monoclonal Mouse anti‑Human MAGEA1 / MAGE 1 Antibody (clone MA454, Azide‑free,BSA‑free, IHC) LS‑C391567
Monoclonal Mouse anti‑Human MAGEA1 / MAGE 1 Antibody (clone MA454, Azide‑free,BSA‑free, IHC) LS‑C391567
Antibody:
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (MA454) Antibody
Application:
IHC-P, Flo
Reactivity:
Human, Rat
Format:
Unconjugated, Azide-free, BSA-free
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
MAGEA1 / MAGE 1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (MA454) Antibody
Application:
IHC-P, Flo
Reactivity:
Human, Rat
Format:
Unconjugated, Azide-free, BSA-free
Other formats:
Specifications
Description
MAGE 1 antibody LS-C391567 is an unconjugated mouse monoclonal antibody to MAGE 1 (MAGEA1) from human. It is reactive with human and rat. Validated for Flow and IHC. Cited in 1 publication.
Target
Human MAGEA1 / MAGE 1
Synonyms
MAGEA1 | Antigen MZ2-E | Cancer/testis antigen 1.1 | CT1.1 | MAGE-1 antigen | MAGE1A | Melanoma antigen family A 1 | Melanoma antigen MAGE-1 | MAGE 1 | MAGE1 | Melanoma-associated antigen 1
Host
Mouse
Reactivity
Human, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Clone
MA454
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free, BSA-free.
Also available Unmodified or Ready-to-Use.
Immunogen
Full length human protein.
Specificity
Human MAGEA1 / MAGE 1
Applications
- IHC - Paraffin (0.5 - 1 µg/ml)
- Flow Cytometry (0.5 - 1 µg/10E6 cells)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Recognizes a protein of 42-46kDa, identified as MAGE-1. This mAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
Presentation
1X PBS
Storage
Store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About MAGEA1 / MAGE 1
LSBio Ratings
MAGEA1 / MAGE 1 Antibody (clone MA454, Azide-free, BSA-free) for IHC, Flow LS-C391567 has an LSBio Rating of
Publications (4)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma. Kenji Murata , Munehide Nakatsugawa , Muhammed A Rahman, Linh T Nguyen, Douglas G Millar, David T Mulder, Kenji Sugata, Hiroshi Saijo, Yukiko Matsunaga, Yuki Kagoya, Tingxi Guo, Mark Anczurowski, Chung-Hsi Wang, Brian D Burt, Dalam Ly, Kayoko Saso, Alexandra Easson, David P Goldstein, Michael Reedijk, Danny Ghazarian, Trevor J Pugh, Marcus O Butler, Tak W Mak, Pamela S Ohashi, Naoto Hirano. eLife. 2020 Apr;9:e53244.
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence
Species:
Human
Applications:
IHC, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Species:
Human
Applications:
IHC, Western blot, ELISA
Reactivity:
Human
Range:
0.625-40 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
