Human LCP2 / SLP-76

Mouse

Human (tested or 100% immunogen sequence identity)

IgG2b Monoclonal

SLP-76/03

Unconjugated

Protein G purified

Unmodified

A fusion protein corresponding to amino acids 216-434 of human SLP-76.

aa216-434

Recognizes the SH2 domain-containing leucocyte protein (SLP-76), a 76kD tyrosine phosphoprotein, expressed primarily by T lymphocytes and cells of the myeloid lineage. SLP-76 is one of several adaptor proteins assisting with TCR-mediated signal transduction, through GRB2 binding, functioning as a substrate for the protein-tyrosine kinase ZAP-70 and thus playing a crucial role in both T cell ontogeny and activation. Other molecules that associate with SLP-76 include phospholipase C (PLC)-gamma, Vav, Nck and fyn binding protein.

• Western blot (1:500)
• Immunoprecipitation

Western Blot: LS-C44763 detects a band of approximately 76kD in T lymphocyte cell lysates.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze/thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q13094 NCBI: NM_005565 NP_005556.1