Target
Human KIR2DL1 / CD158a
Synonyms
KIR2DL1 | 47.11 | Cl-42 | MHC class I NK cell receptor | NKAT-1 | p58 NK receptor CL-42/47.11 | NKAT | NKAT1 | p58.1 | CD158A | CD158a antigen | Killer Ig receptor | KIR-K64 | KIR221
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Phycoerythrin.
Also available
Unconjugated or conjugated with
Biotin,
FITC,
HRP.
Immunogen
Human natural killer (NK) cell lysate.
Specificity
Recognizes KIR2D members of the killer cell immunoglobulin (Ig)-like receptor (KIR) family: CD158a, CD158b and P50.3. Specifically recognizes the long and short forms CD158a and CD158b (KIR2DL, KIR2DS1 and KIR2DS2 respectively) and also p50.3 (KIR2DS4). Reported to have functional activity, activating NK cell cytotoxicity via KIR2DS and inhibiting via KIR2DL forms.