Target
Human KCNC1 / Kv3.1
Synonyms
KCNC1 | KShIIIB | KV3.1 | Raw2 | Shaw22 | KV4 | NGK2
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
Biotin,
FITC.
Immunogen
Recombinant Human Potassium voltage-gated channel subfamily C member 1 protein (1-190AA)
Specificity
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons.