Human ITGAX / CD11c

Mouse

Human (tested or 100% immunogen sequence identity)

IgG2a Monoclonal

CBR-p150/4G1

Unconjugated

Affinity purified

Preservative Free. Also available Unmodified.

Recombinant human CD11c.

Recognizes human CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150,95, a 150kD type I transmembrane protein and member of the integrin alpha chain family, expressed by monocytes, macrophages, granulocytes and NK cells, and is a marker for hairy cell leukaemia cells. CD11c combines with the CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, acts as a mediator of leukocyte adherence to endothelium, and binds to the ligands CD54 (ICAM1), iC3b and fibrinogen. Clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. Does not recognize CD11a, CD11b or CD18.

• IHC - Frozen (5 - 10 µg/ml)
• Flow Cytometry

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.

PBS

Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P20702 NCBI: NM_000887 NP_000878.2