Target
Human IL6R / IL6 Receptor
Synonyms
IL6R | CD126 | gp80 | IL-6R subunit alpha | IL-6R-alpha | IL-6RA | IL6Q | IL-6 receptor subunit alpha | IL-6R 1 | IL-6R-1 | Interleukin 6 receptor | Membrane glycoprotein 80 | CD126 antigen | IL6RA | IL6RQ
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Recombinant Monoclonal
Clone
rhPM-1 (Tocilizumab)
Conjugations
Unconjugated
Purification
Protein A purified
Immunogen
This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
Specificity
Tocilizumab binds specifically to both the membrane bound and soluble forms of human IL-6R. The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response.
Usage
Applications should be user optimized.
Presentation
PBS, 0.02% ProClin™ 300.
Storage
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About IL6R / IL6 Receptor