Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Location
Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Telephone Numbers
Customer Service: (800) 227-6666 / (650) 697-3600
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
| Catalog Number | Size | Price |
|---|---|---|
| LS-B4912-0.1 | 0.1 mg (0.5 mg/ml) | $495 |
IHC‑plus™ Monoclonal Rat anti‑Mouse IL17 Antibody (clone TC11‑18H10, IHC, WB) LS‑B4912
IHC‑plus™ Monoclonal Rat anti‑Mouse IL17 Antibody (clone TC11‑18H10, IHC, WB) LS‑B4912
Note: This antibody replaces LS-C41753
Antibody:
IL17 Rat anti-Mouse Monoclonal (TC11-18H10) Antibody
Application:
IHC, IHC-P, WB, Flo, ELISA
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
IL17 Rat anti-Mouse Monoclonal (TC11-18H10) Antibody
Application:
IHC, IHC-P, WB, Flo, ELISA
Reactivity:
Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
IL17 antibody LS-B4912 is an unconjugated rat monoclonal antibody to mouse IL17. Validated for ELISA, Flow, IHC and WB. Cited in 2 publications.
Host
Rat
Reactivity
Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
TC11-18H10
Conjugations
Unconjugated
Purification
Purified from ascites.
Modifications
Unmodified
Immunogen
E. coli-expressed, recombinant mouse IL-17A
Specificity
Recognizes mouse Interleukin 17, a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot
- Flow Cytometry
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
ELISA: This antibody can be used in a sandwich ELISA with LS-C41752 as a detection antibody.
Presentation
BBS
Storage
Store at -20°C. Avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only. Intended for use by laboratory professionals.
Validation
Anti-IL-17 antibody IHC of mouse spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-IL-17 antibody IHC of mouse spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ IL17 Antibody (clone TC11-18H10) for IHC, WB/Western, Flow, ELISA LS-B4912 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (2)
Role of IL-17A in Chronic Rhinosinusitis With Nasal Polyp. Gwanghui Ryu , Jun Sang Bae , Ji Hye Kim, Eun Hee Kim, Lele Lyu, Young Jun Chung, Ji Hun Mo. Allergy, asthma & immunology research. 2020 May;12:507-522.
Particulate Matter Exposure Aggravates IL-17-Induced Eye and Nose Inflammation in an OVA/Poly(I:C) Mouse Model. Jun-Sang Bae , Soo Bin Oh , Jeongyun Kim, Hoon Kim, Ji Hye Kim, Eun-Hee Kim, Kyong Jin Cho, Ji-Hun Mo. Allergy, asthma & immunology research. 2022 January;14:59-72.
Customer Reviews (0)
Featured Products
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
