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| Catalog Number | Size | Price |
|---|---|---|
| LS-B6236-50 | 50 µg (1 mg/ml) | $485 |
IHC‑plus™ Monoclonal Mouse anti‑Human HTT / Huntingtin Antibody (aa2703‑2911, IHC, WB) LS‑B6236
IHC‑plus™ Monoclonal Mouse anti‑Human HTT / Huntingtin Antibody (aa2703‑2911, IHC, WB) LS‑B6236
Note: This antibody replaces LS-C24586
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
Huntingtin antibody LS-B6236 is an unconjugated mouse monoclonal antibody to Huntingtin (HTT) (aa2703-2911) from human. It is reactive with human and rabbit. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Target
Human HTT / Huntingtin
Synonyms
HTT | Huntingtin | Huntington disease protein | IT15 | HD | HD protein
Host
Mouse
Reactivity
Human, Rabbit
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant protein corresponding to aa 2703-2911 of huntingtin.
Epitope
aa2703-2911
Specificity
Reacts with an epitope corresponding to the human HDC region (2703-2911 amino acids) of the huntingtin protein. Detects a 350kD band on Western Blots but also detects smaller degradation products of Huntingtin. Recognizes both denatured and native Huntingtin in human brain. The combined use of this antibody, LS-C24585 and LS-demonstrates that huntingtin is enriched in neuronal cells in the brain.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- IHC - Frozen
- Western blot
- Immunoprecipitation
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot. Immunohistochemistry: Frozen, FFPE (human). Increased cytoplasmic staining, relative to nuclear, has been reported using formaldehyde as a fixative compared with acetone/methanol. Positive control: IHC frozen-rabbit btain.
Presentation
PBS, 0.09% Sodium Azide
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HTT / Huntingtin
Validation
Anti-HTT / Huntingtin antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-HTT / Huntingtin antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ HTT / Huntingtin Antibody (aa2703-2911) for IHC, WB/Western, IP LS-B6236 has an LSBio Rating of
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human, Mouse
Applications:
IHC, Western blot
Species:
Human, Monkey, Rat
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, Immunoprecipitation, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/15/2024
Date Requested: 11/15/2024
