Human B2M / Beta 2 Microglobulin

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

2213

Unconjugated

Protein A purified

Unmodified

Highly pure beta-2-microglobulin from human urine

Recognizes native human beta 2 microglobulin, a 119 amino acid component of MHC class I molecules present on all nucleated cells, containing a single domain, Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients. Also known as B2M, it has been suggested that this protein can be used as a prognostic marker for HIV infection.

• IHC
• IHC - Paraffin (5 µg/ml)
• ELISA

Immunohistochemistry: LS-B2249 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2249 was determined to be 5 ug/ml.

PBS, 0.05% Sodium Azide, 10% Glycerol

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P61769 NCBI: NM_004048 NP_004039.1