Human IFNA2 / Interferon Alpha 2

Mouse

Human (tested or 100% immunogen sequence identity)

IgG,k Monoclonal

N39

Unconjugated

Protein G purified

Azide-free, BSA-free. Also available Unmodified.

Purified recombinant human IFNA2.

Human IFNA2 / Interferon Alpha 2

• Immunofluorescence (1 - 2 µg/ml)
• Flow Cytometry (0.5 - 1 µg/10E6 cells)

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN- (II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This mAb is specific for IFN- (II) and does not cross-react with IFN- (I). The site recognized by this mAb is called "site I" and is responsible for the antiviral and anti-proliferative activities of IFN- (II). Epitopes of N27 and N39 mAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN- (II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens. Optimal dilution of the Interferon alpha 2 antibody should be determined by the researcher.

1X PBS

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P01563 NCBI: NM_000605 NP_000596.2