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| Catalog Number | Size | Price |
|---|---|---|
| LS-C388615-100 | 100 µg | $575 |
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Polyclonal Rabbit anti‑Rat HSPD1 / HSP60 Antibody (aa503‑516, IHC, WB) LS‑C388615
Polyclonal Rabbit anti‑Rat HSPD1 / HSP60 Antibody (aa503‑516, IHC, WB) LS‑C388615
Antibody:
HSPD1 / HSP60 Rabbit anti-Rat Polyclonal (aa503-516) Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Rat, Mouse, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Sheep
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
HSPD1 / HSP60 Rabbit anti-Rat Polyclonal (aa503-516) Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Rat, Mouse, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Sheep
Format:
Unconjugated, Unmodified
Specifications
Description
HSP60 antibody LS-C388615 is an unconjugated rabbit polyclonal antibody to HSP60 (HSPD1) (aa503-516) from rat. It is reactive with mouse, rat, bovine and other species. Validated for ICC, IHC and WB.
Target
Rat HSPD1 / HSP60
Synonyms
HSPD1 | 60 kDa chaperonin | CPN60 | Heat shock protein 65 | Heat shock protein 60 | HSP-60 | HSP60 | HuCHA60 | HLD4 | HSP65 | p60 lymphocyte protein | SPG13 | Chaperonin 60 | GROEL
Host
Rabbit
Reactivity
Rat, Mouse, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Sheep
(tested or 100% immunogen sequence identity)
Predicted
Human, Bat, Guinea pig, Chicken (at least 90% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from the C-Terminus of rat HSP60 (YDAMLGDFVNMVEK, aa503-516 of UniProt P63039). Percent identity by BLAST analysis: Mouse, Rat, Ferret, Sheep, Cat, Bovine, Hamster, Elephant, Rabbit, Horse, Pig, Turkey, Zebra finch, Dog (100%); Human, Bat, Opossum, Guinea pig, Chicken, Lizard (93%); Stickleback (86%).
Epitope
aa503-516
Specificity
Rat HSPD1 / HSP60
Applications
- IHC
- IHC - Paraffin (0.5 - 1 µg/ml)
- ICC (0.5 - 1 µg/ml)
- Western blot (0.5 - 1 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Heat shock 60KD protein is a member of the chaperonin class of protein factors and the nuclear encoded mitochondrial HSP60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. HSP60 is linked head to head comprising approximately 17 kb and consist of 12 exons. It can downregulate adaptive immune responses by upregulating Tregs innately throughTLR2signaling. Variations in secondary/substrate sensitivities and test protocols may require the HSP60 antibody to be titrated for optimal performance.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HSPD1 / HSP60
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 6/30/2024
Date Requested: 6/30/2024
