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| Catalog Number | Size | Price |
|---|---|---|
| LS-B2441-50 | 50 µg (5.7 mg/ml) | $645 |
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IHC‑plus™ Polyclonal Rabbit anti‑Human HPSE / Heparanase Antibody (IHC, WB) LS‑B2441
IHC‑plus™ Polyclonal Rabbit anti‑Human HPSE / Heparanase Antibody (IHC, WB) LS‑B2441
Note: This antibody replaces LS-C24191, LS-C67434
Antibody:
HPSE / Heparanase Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
HPSE / Heparanase Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
Heparanase antibody LS-B2441 is an unconjugated rabbit polyclonal antibody to Heparanase (HPSE) from human. It is reactive with human and mouse. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Target
Human HPSE / Heparanase
Synonyms
HPSE | Endo-glucoronidase | Heparanase-1 | Heparanase | HPA | HSE1 | HEP | HPA1 | HPSE1 | HPR1
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
A heterodimeric recombinant protein consisting of the 50 kDa and 8 kDa subunits.
Specificity
Recognizes the 65kD precursor as well as the 50kD and 8kD subunits of human or mouse Heparanase.
Applications
- IHC
- IHC - Paraffin (5 µg/ml)
- Western blot (1:2000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B2441 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2441 was determined to be 5 ug/ml. Western Blot: 1:1000.
Presentation
PBS, pH 7.2, 0.01% Thimerosal
Storage
Short term: 4°C Long term: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HPSE / Heparanase
Validation
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Negative Staining in Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Negative Staining in Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
IHC-plus™ HPSE / Heparanase Antibody for IHC, WB/Western LS-B2441 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (1)
Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth. Spyrou A, Kundu S, Haseeb L, Yu D, Olofsson T, Dredge K, Hammond E, Barash U, Vlodavsky I, Forsberg-Nilsson K. Molecular cancer therapeutics. 2017 August;16:1705-1716.
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, Western blot, ELISA
Species:
Human
Applications:
Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
Western blot
Reactivity:
Human
Range:
31.2-2000 pg/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/21/2024
Date Requested: 12/21/2024
