Target
Human HPSE / Heparanase
Synonyms
HPSE | Endo-glucoronidase | Heparanase-1 | Heparanase | HPA | HSE1 | HEP | HPA1 | HPSE1 | HPR1
Reactivity
Human, Rat
(tested or 100% immunogen sequence identity)
Purification
Immunogen affinity purified
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Heparanase 1 (301-331 aa NGRTATKEDFLNPDVLDIFISSVQKVFQVVE), different from the related mouse and rat sequences by eight amino acids.
Specificity
Highly expressed in placenta and spleen and weakly expressed in lymph node, thymus, peripheral blood leukocytes, bone marrow, endothelial cells, fetal liver and tumor tissues. Also expressed in hair follicles, specifically in both Henle's and Huxley's layers of inner the root sheath (IRS) at anagen phase. .