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| Catalog Number | Size | Price |
|---|---|---|
| LS-C744231-5 | 5 ml | $363 |
Monoclonal Mouse HMB45 Antibody (clone HMB45, IHC) LS‑C744231
Monoclonal Mouse HMB45 Antibody (clone HMB45, IHC) LS‑C744231
Antibody:
HMB45 Mouse Monoclonal (HMB45) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
HMB45 Mouse Monoclonal (HMB45) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
HMB45 antibody LS-C744231 is an unconjugated mouse monoclonal antibody to human HMB45. Validated for IHC.
Target
HMB45
Synonyms
HMB45 | PMEL17 | HMB-45 | HMB 45 | Human Melanoma Black | melanosomal glycoprotein gp100
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
HMB45
Conjugations
Unconjugated
Modifications
Unmodified
Immunogen
Extract from lymph node metastases of melanoma
Applications
- IHC - Paraffin
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Pre-treatment with pronase 0.1% or antigen retrieval The antibody HMB45 is used for the discrimination of Melanoma from normal Melanocytes. Melanoic Schwannoma Clear Cell Sarcoma will also be stained. Negative are tumours of epithelial, lymphoid, glial and mesenchymal origin. Melanocytes are pigmented, melanin containing cells being located mainly in the epidermis. They protect tissues from UVB irradiation of the sun. The antibody HMB45 reacts with fetal and neonatal Melanocytes, with junctional and blue naevus cells, but not with intradermal naevi and adult melanocytes. Neuraminidase-sensitive glycoconjugate on the surface of human melanosomes.
Presentation
PBS, pH 7.3, 0.09% Sodium Azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Publications (0)
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Species:
Human
Applications:
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/25/2024
Date Requested: 12/25/2024
