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Catalog Number Size Price
LS-C391953-100 100 µg (1 mg/ml) $574 
HLA-DRB1 Antibody - IHC testing of FFPE human histiocytoma and HLA-DRB1 antibody (clone MHDRb2).  This image was taken for the unmodified form of this product. Other forms have not been tested.
HLA-DRB1 Antibody - IHC testing of FFPE human tonsil and HLA-DRB1 antibody (clone MHDRb2).  This image was taken for the unmodified form of this product. Other forms have not been tested.
HLA-DRB1 Antibody - Western blot testing of Ramos lysate and HLA-DRB1 antibody (clone MHDRb2). Predicted molecular weight ~28 kDa.  This image was taken for the unmodified form of this product. Other forms have not been tested.
HLA-DRB1 Antibody - IHC testing of FFPE human histiocytoma and HLA-DRB1 antibody (clone MHDRb2).  This image was taken for the unmodified form of this product. Other forms have not been tested.
HLA-DRB1 Antibody - IHC testing of FFPE human tonsil and HLA-DRB1 antibody (clone MHDRb2).  This image was taken for the unmodified form of this product. Other forms have not been tested.
HLA-DRB1 Antibody - Western blot testing of Ramos lysate and HLA-DRB1 antibody (clone MHDRb2). Predicted molecular weight ~28 kDa.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Monoclonal Mouse anti‑Human HLA‑DRB1 Antibody (clone MHDRb2, Azide‑free,BSA‑free, IHC, IF, WB) LS‑C391953

Monoclonal Mouse anti‑Human HLA‑DRB1 Antibody (clone MHDRb2, Azide‑free,BSA‑free, IHC, IF, WB) LS‑C391953

Antibody:
HLA-DRB1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (MHDRb2) Antibody
Application:
IHC, IHC-P, IF, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Azide-free, BSA-free
Other formats:
Price
Catalog Number
$574
LS-C391953-100
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
HLA-DRB1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (MHDRb2) Antibody
Application:
IHC, IHC-P, IF, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Azide-free, BSA-free
Other formats:

Specifications

Description
HLA-DRB1 antibody LS-C391953 is an unconjugated mouse monoclonal antibody to human HLA-DRB1. Validated for Flow, IF, IHC and WB.
Target
Human HLA-DRB1
Synonyms
HLA-DRB1 | DRB1 | HLA-DR1B | HLA-DRB | Human leucocyte antigen DRB1 | MHC class II antigen DRB1*10 | MHC class II antigen | MHC class II antigen DRB1*1 | HLA-DRB2 | Lymphocyte antigen DRB1 | SS1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal
Clone
MHDRb2
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free, BSA-free. Also available Unmodified or Ready-to-Use.
Immunogen
Activated human peripheral blood mononuclear cells were used as the immunogen for the HLA-DRB1 antibody.
Specificity
Human HLA-DRB1
Applications
  • IHC
  • IHC - Paraffin (0.25 - 0.5 µg/ml)
  • Immunofluorescence (0.5 - 1 µg/ml)
  • Western blot (0.5 - 1 µg/ml)
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide. exons 2 and 3 encode the two extracellular domains. exon 4 encodes the transmembrane domain. and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. [RefSeq] Optimal dilution of the HLA-DRB1 antibody should be determined by the researcher. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
Presentation
1X PBS
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About HLA-DRB1
P01911 NM_002124 NP_002115.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/23/2024