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| Catalog Number | Size | Price |
|---|---|---|
| LS-C313254-10 | 10 µg | $318 |
| LS-C313254-100 | 100 µg (0.5 mg/ml) | $470 |
1 of 2
2 of 2
Polyclonal Rabbit anti‑Human HIF3A / HIF3‑Alpha Antibody (aa497‑514, WB) LS‑C313254
Polyclonal Rabbit anti‑Human HIF3A / HIF3‑Alpha Antibody (aa497‑514, WB) LS‑C313254
Note: This antibody replaces LS-C388568
Antibody:
HIF3A / HIF3-Alpha Rabbit anti-Human Polyclonal (aa497-514) Antibody
Application:
WB
Reactivity:
Human, Monkey, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
HIF3A / HIF3-Alpha Rabbit anti-Human Polyclonal (aa497-514) Antibody
Application:
WB
Reactivity:
Human, Monkey, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
HIF3-Alpha antibody LS-C313254 is an unconjugated rabbit polyclonal antibody to HIF3-Alpha (HIF3A) (aa497-514) from human. It is reactive with human, rat and monkey. Validated for WB.
Target
Human HIF3A / HIF3-Alpha
Synonyms
HIF3A | BHLHe17 | HIF-3A | IPAS | HIF3-alpha-1 | Inhibitory PAS domain protein | PASD7 | HIF-3-alpha | HIF3-alpha | Member of PAS protein 7 | MOP7
Host
Rabbit
Reactivity
Human, Monkey, Rat
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunogen affinity purified
Modifications
Unmodified
Immunogen
A synthetic peptide corresponding to a sequence at the C-Terminus of human HIF3(497-514 aa DDDFQLNASEQLPRAYHR), different from the related rat and mouse sequences by five amino acids.
Epitope
aa497-514
Specificity
Expressed in vascular cells (at protein level) (PubMed:21069422). Expressed in kidney (PubMed:11573933, PubMed:19694616). Expressed in lung epithelial cells (PubMed:16775626). Expressed in endothelial cells (venous and arterial cells from umbilical cord and aortic endothelial cells) and in vascular smooth muscle cells (aorta) (PubMed:21069422). Strongly expressed in the heart, placenta, and skeletal muscle, whereas a weak expression profile was found in the lung, liver, and kidney (PubMed:12538644). Expressed weakly in cell renal cell carcinoma (CC-RCC) compared to normal renal cells (PubMed:16126907). Expression is down-regulated in numerous kidney tumor cells compared to non tumor kidney tissues (PubMed:16126907). Isoform 2 is expressed in heart, placenta, lung, liver, skeletal muscle and pancreas and in numerous cancer cell lines (PubMed:20416395). Isoform 3 and isoform 4 are weakly expressed in heart, placenta, lung, liver, skeletal muscle and pancreas (PubMed:20416395). Isoform 4 is expressed in fetal tissues, such as heart, brain, thymus, lung, liver, skeletal kidney and spleen (PubMed:20416395). Isoform 3 is weakly expressed in fetal tissues, such as liver and kidney (PubMed:20416395). .
Applications
- Western blot
Presentation
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg Thimerosal, 0.05mg sodium azide.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500µg/ml.
Storage
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HIF3A / HIF3-Alpha
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Mouse
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Mouse, Rat
Applications:
Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 3/15/2025
Date Requested: 3/15/2025
