Target
Pig GPX5
Synonyms
GPX5 | EGLP | GPx-5 | GSHPx-5 | epididymal androgen-related protein | epididymis secretory sperm binding protein Li 75p
Reactivity
Pig
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated.
Also available conjugated with
HRP,
FITC,
Biotin.
Immunogen
Recombinant Pig Epididymal secretory glutathione peroxidase protein (22-219AA)
Specificity
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction.