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GPR44 / CRTH2
prostaglandin D2 receptor 2
Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca2+ mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
| Gene Name: | prostaglandin D2 receptor 2 |
| Family/Subfamily: | GPCR , Prostanoid |
| Synonyms: | PTGDR2, CD294, CRTH2, CD294 antigen, DP2, DL1R, G protein-coupled receptor 44, G-protein coupled receptor 44, HCRTH2, DP2 prostaglandin receptor, GPR44, Prostaglandin D2 receptor 2 |
| Target Sequences: | NM_004778 NP_004769.2 Q9Y5Y4 |
☰ Filters
Products
Antibodies
(19)
Proteins
(2)
Type
Over-Expression Lysate
(2)
Primary
(19)
Target
GPR44 / CRTH2
(21)
Reactivity
Human
(18)
Mouse
(7)
Rat
(3)
Monkey
(2)
Application
IHC
(7)
IHC-P
(6)
WB
(12)
Flo
(2)
ELISA
(7)
ICC
(2)
IF
(2)
Peptide-ELISA
(1)
Host
rabbit
(15)
mouse
(4)
Product Group
GPCR Database Antibodies
(4)
IHCPlus
(2)
PathPlus Neuro
(2)
Isotype
IgG
(9)
IgG2b,k
(4)
Clonality
monoclonal mc
(4)
polyclonal pc
(15)
Clone
54N1H4
(1)
54N3F8
(1)
Format
Preservative Free
(1)
Unconjugated
(19)
Epitope
Extracellular Domain
(2)
151-200 aa, Internal
(1)
Asp113
(1)
C-Terminus
(1)
N-Terminal
(1)
N-Terminus
(1)
Publications
No
(21)
Tag
Myc-DDK (Flag)
(2)
Species
Human
(1)
Source
293T Cells
(1)
HEK 293 Cells
(1)
Neuroscience
Fast Shipping
GPR44 / CRTH2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human, Monkey
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
Neuroscience
Fast Shipping
GPR44 / CRTH2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
GPR44 / CRTH2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
GPR44 / CRTH2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$395
GPR44 / CRTH2 Mouse anti-Human Monoclonal (54N3F8) Antibody
Human
WB
Unconjugated
0.1 mg/$386
GPR44 / CRTH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
GPR44 / CRTH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
0.1 mg/$460
GPR44 / CRTH2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$282; 200 µl/$350
GPR44 / CRTH2 Rabbit anti-Human Polyclonal (N-Terminal) Antibody
Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$523
GPR44 / CRTH2 Mouse anti-Human Monoclonal Antibody
Human
Flo, WB
Unconjugated
25 µg/$288; 100 µg/$414
GPR44 / CRTH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
GPR44 / CRTH2 Rabbit anti-Human Polyclonal (151-200 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GPR44 / CRTH2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
GPR44 / CRTH2 Mouse anti-Human Monoclonal Antibody
Human
Flo
Unconjugated
25 µg/$288; 100 µg/$414
GPR44 / CRTH2 Mouse anti-Human Monoclonal (54N1H4) Antibody
Human
WB
Unconjugated
0.1 mg/$386
GPR44 / CRTH2 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
IHC-P
Unconjugated, Preservative Free
100 µl/$302
GPR44 / CRTH2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$444; 100 µg/$597
GPR44 / CRTH2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$475
GPR44 / CRTH2 Rabbit anti-Human Polyclonal (Asp113) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
293T Cells
Myc-DDK (Flag)
43.7 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
43.7 kDa
100 µg/$494
Viewing 1-21
of 21
product results
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