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| Catalog Number | Size | Price |
|---|---|---|
| LS-C498919-50 | 50 µg (3 mg/ml) | $294 |
| LS-C498919-100 | 100 µg (3 mg/ml) | $360 |
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Polyclonal Rabbit anti‑Human GCGR / Glucagon Receptor Antibody (aa26‑136, IHC, IF, WB) LS‑C498919
Polyclonal Rabbit anti‑Human GCGR / Glucagon Receptor Antibody (aa26‑136, IHC, IF, WB) LS‑C498919
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
Glucagon Receptor antibody LS-C498919 is an unconjugated rabbit polyclonal antibody to Glucagon Receptor (GCGR) (aa26-136) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
Target
Human GCGR / Glucagon Receptor
Synonyms
GCGR | GL-R | Glucagon receptor | GGR
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Glucagon receptor protein (26-136AA)
Epitope
aa26-136
Specificity
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Applications
- IHC
- Immunofluorescence
- Western blot
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: store at -20°C. Long term: store at -80°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About GCGR / Glucagon Receptor
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
