GAD65

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

GAD65 is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

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Products

Antibodies (91)

ELISA Kits (20)

Proteins (16)

Type

Custom (3)

Development Kit (3)

Over-Expression Lysate (4)

Primary (91)

Recombinant (12)

Sandwich (12)

Sandwich CLIA (2)

Target

GAD65 (127)

Reactivity

Human (66)

Mouse (34)

Rat (50)

Bovine (1)

Chicken (1)

Dog (1)

Horse (1)

Monkey (2)

Pig (1)

Porcine (1)

Rabbit (2)

Sheep (1)

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Application

IHC (18)

IHC-P (15)

WB (74)

Flo (2)

ELISA (27)

ICC (7)

IF (13)

IP (5)

Peptide-ELISA (1)

RIA (2)

Host

rabbit (66)

mouse (24)

goat (1)

Product Group

DevKit DuoPlus (3)

IHCPlus (3)

Isotype

IgG (39)

IgG1 (9)

IgG2a,k (1)

IgG2b,k (5)

Clonality

monoclonal mc (23)

polyclonal pc (68)

Clone

144 (2)

3G3 (1)

5D9G12 (1)

5D9G9 (1)

GAD2/1960 (2)

GAD2/2362 (3)

N-GAD65 (1)

TS106 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (15)

Antibody Pair and Standard (3)

APC (4)

APC Conjugated (6)

Azide-free (3)

Biotin Conjugated (9)

BSA-free (2)

Cy3 Conjugated (4)

Cy7 Conjugated (4)

FITC Conjugated (9)

HRP Conjugated (9)

PE Conjugated (6)

Preservative Free (1)

Ready-to-Use (1)

RPE Conjugated (1)

Unconjugated (43)

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Epitope

aa1-150 (16)

aa109-138 (8)

aa188-374 (8)

aa65-105 (8)

N-Terminus (6)

aa1-585 (4)

Asp572 (1)

aa21-37 (1)

aa4-22 (1)

aa445-473 (1)

aa465-558 (1)

aa515-528 (1)

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Publications

No (127)

Sample Type

Biological Fluids (1)

Cell Culture Supernatants (5)

Cell Lysates (4)

Cell Supernatant (1)

Plasma (11)

Serum (11)

Tissue Homogenates (8)

Tag

6His, N-terminus (1)

GST (3)

His, N-Terminal (1)

His/GST,N-terminus (1)

His-GST (1)

His-S (2)

Myc-DDK (Flag) (6)

Species

Human (9)

Mouse (3)

Rat (2)

Source

293T Cells (2)

Baculovirus (2)

E. coli (5)

HEK 293 Cells (4)

Insect Cells (1)

Wheat Germ Extract (2)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (3)

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IHC-plus™ GAD65 Antibody (aa515-528) LS-B3937

(4.0) Rating

Antibody:

GAD65 Goat anti-Human Polyclonal (aa515-528) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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GAD65 Antibody (aa465-558) LS-C185356

Antibody:

GAD65 Rabbit anti-Human Polyclonal (aa465-558) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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Human GAD65 (Sandwich ELISA) ELISA Kit - LS-F4508

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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Human GAD65 (Sandwich ELISA) ELISA Kit - LS-F13874

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Mouse GAD65 (Sandwich ELISA) ELISA Kit - LS-F13878

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Biological Fluids, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Human GAD65 (Sandwich ELISA) ELISA Kit - LS-F33968

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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GAD65 Antibody (aa445-473) LS-C159699

Antibody:

GAD65 Mouse anti-Human Monoclonal (aa445-473) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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GAD65 Antibody LS-C109497

Antibody:

GAD65 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$450

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Human GAD65 (CLIA) ELISA Kit - LS-F29863

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Mouse GAD65 Protein (Recombinant) (Met1-Leu585) - LS-G98163

Source:

Baculovirus

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

65.4 kDa

Price:

20 µg/$649

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Human GAD65 Protein (Recombinant His-GST) (aa65-105) - LS-G13568

Source:

E. coli

Tag:

His-GST

Molecular Weight:

36.1 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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IHC-plus™ GAD65 Antibody (aa4-22, clone N-GAD65) LS-B9984

(4.0) Rating

Antibody:

GAD65 Mouse anti-Human Monoclonal (aa4-22) (N-GAD65) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, RIA, WB

Format:

Unconjugated

Price:

50 µg/$460

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GAD65 Antibody (aa109-138) LS-C321534

Antibody:

GAD65 Rabbit anti-Human Polyclonal (aa109-138) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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GAD65 Antibody (aa109-138, APC) LS-C214558

Antibody:

GAD65 Rabbit anti-Human Polyclonal (aa109-138) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• APC

• Unconjugated
• APC

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GAD65 Antibody LS-C331171

Antibody:

GAD65 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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Rat GAD65 (Sandwich ELISA) ELISA Kit - LS-F21541

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Monkey GAD65 (Sandwich ELISA) ELISA Kit - LS-F44382

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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GAD65 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122977

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.2 kDa

Price:

100 µg/$710

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Human GAD65 Protein (Recombinant His, N-Terminal) (Met188-Ser374) - LS-G132984

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

21.6kDa

Price:

10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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GAD65 Antibody LS-C665717

Antibody:

GAD65 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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GAD65 Antibody (aa21-37) LS-C312569

Antibody:

GAD65 Rabbit anti-Human Polyclonal (aa21-37) Antibody

Reactivity:

Rabbit, Mouse, Sheep, Bovine, Rat, Horse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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GAD65 Antibody (clone 5D9G9) LS-C669313

Antibody:

GAD65 Mouse anti-Human Monoclonal (5D9G9) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$459

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GAD65 Antibody (clone 3G3) LS-C197265

Antibody:

GAD65 Mouse anti-Human Monoclonal (3G3) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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GAD65 Antibody (aa109-138) LS-C159700

Antibody:

GAD65 Mouse anti-Human Monoclonal (aa109-138) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

0.1 ml/$393

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GAD65 Antibody (aa109-138) LS-C166333

Antibody:

GAD65 Rabbit anti-Human Polyclonal (aa109-138) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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