Target
Human FOXE2 / FOXE1
Synonyms
FOXE1 | FKHL15 | Forkhead related protein 15 | Forkhead box e1 | Forkhead box E2 | Forkhead box protein E2 | FOXE2 | HNF-3/fork head-like protein 5 | TITF2 | TTF-2 | Thyroid transcription factor 2 | Forkhead box protein E1 | HFKH4 | HFKL5
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated.
Also available conjugated with
HRP,
Biotin,
FITC.
Immunogen
Recombinant Human Forkhead box protein E1 protein (184-365AA)
Specificity
Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression.