Target
Human Fibulin-3 / EFEMP1
Synonyms
EFEMP1 | DHRD | Extracellular protein S1-5 | FBNL | FBLN3 | Fibrillin-like protein | Fibrillin-like | MLVT | S1-5 | MTLV | DRAD | FIBL-3 | Fibulin-3
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
FITC,
Biotin.
Immunogen
Recombinant human EGF-containing fibulin-like extracellular matrix protein 1 protein (27-184AA)
Specificity
Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.