Target
Human ELOVL4
Synonyms
ELOVL4 | Cancer/testis antigen 118 | CT118 | ELOVL FA elongase 4 | ADMD | ISQMR | STGD2 | STGD3 | ELOVL fatty acid elongase 4
Reactivity
Human
(tested or 100% immunogen sequence identity)
Immunogen
Recombinant Human Elongation of very long chain fatty acids protein 4 protein (270-314AA)
Specificity
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.