EHMT1

euchromatic histone-lysine N-methyltransferase 1

Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53.

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Products

Antibodies (46)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (46)

Recombinant (1)

Target

EHMT1 (49)

Reactivity

Human (46)

Mouse (2)

Rat (1)

Application

IHC (1)

IHC-P (1)

WB (46)

ELISA (37)

IF (5)

IP (1)

Peptide-ELISA (1)

Host

rabbit (39)

mouse (7)

Isotype

IgG (33)

IgG1 (1)

IgG2a,k (6)

Clonality

monoclonal mc (7)

polyclonal pc (39)

Format

APC Conjugated (6)

Azide-free (5)

Biotin Conjugated (6)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (6)

Unconjugated (16)

Epitope

aa1145-1174 (7)

aa195-226 (7)

aa203-233 (7)

aa367-396 (7)

aa979-1010 (7)

aa1-101 (1)

aa25-75 (1)

Publications

No (49)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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EHMT1 Antibody (aa25-75) LS-C288432

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa25-75) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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EHMT1 Antibody (aa1145-1174) LS-C96520

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa1145-1174) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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Human EHMT1 Protein (Recombinant GST, N-terminus) (Full Length) - LS-G35293

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Molecular Weight:

113.1 kDa

Price:

10 µg/$479; 25 µg/$670

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EHMT1 Antibody (aa1-101) LS-C307360

Antibody:

EHMT1 Mouse anti-Human Monoclonal (aa1-101) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$705

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EHMT1 Antibody (HRP) LS-C541945

Antibody:

EHMT1 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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EHMT1 Antibody (Biotin) LS-C521812

Antibody:

EHMT1 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

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EHMT1 Antibody (FITC) LS-C531856

Antibody:

EHMT1 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

FITC Conjugated

Price:

100 µl/$904

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EHMT1 Antibody (PE) LS-C650054

Antibody:

EHMT1 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

PE Conjugated

Price:

100 µl/$904

Select

EHMT1 Antibody (APC) LS-C513596

Antibody:

EHMT1 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

EHMT1 Antibody LS-C812445

Antibody:

EHMT1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

Select

EHMT1 Antibody (aa203-233) LS-C327322

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa203-233) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

EHMT1 Antibody (aa203-233, FITC) LS-C277199

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa203-233) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

EHMT1 Antibody (aa203-233, Azide-free, HRP) LS-C277200

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa203-233) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

EHMT1 Antibody (aa203-233, PE) LS-C277201

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa203-233) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

EHMT1 Antibody (aa203-233, APC) LS-C277198

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa203-233) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• FITC
• HRP, Azide-free
• PE
• APC

• Unconjugated
• FITC
• HRP, Azide-free
• More...
  • PE
  • APC

Select

EHMT1 Antibody (aa367-396) LS-C327324

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa367-396) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

EHMT1 Antibody (aa367-396, PE) LS-C277211

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa367-396) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• PE

• Unconjugated
• PE

Select

EHMT1 Antibody (aa1145-1174) LS-C327323

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa1145-1174) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

EHMT1 Antibody (aa1145-1174, FITC) LS-C277204

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa1145-1174) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

EHMT1 Antibody (aa1145-1174, Azide-free, HRP) LS-C277205

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa1145-1174) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

EHMT1 Antibody (aa1145-1174, APC) LS-C277203

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa1145-1174) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

EHMT1 Antibody (aa1145-1174, PE) LS-C277206

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa1145-1174) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• FITC
• HRP, Azide-free
• More...
  • APC
  • PE

Select

EHMT1 Antibody (aa195-226) LS-C327327

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa195-226) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

EHMT1 Antibody (aa979-1010) LS-C327326

Antibody:

EHMT1 Rabbit anti-Human Polyclonal (aa979-1010) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

EHMT1 Antibody LS-C804101

Antibody:

EHMT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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