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| Catalog Number | Size | Price |
|---|---|---|
| LS-C6611-100 | 100 µg | $845 |
Monoclonal Mouse anti‑Human EGFR Antibody (phospho‑Tyr1173, WB) LS‑C6611
Monoclonal Mouse anti‑Human EGFR Antibody (phospho‑Tyr1173, WB) LS‑C6611
Antibody:
EGFR Mouse anti-Human Monoclonal (pTyr1173) Antibody
Application:
WB, IP, ELISA
Reactivity:
Human, Mouse, Rat, Dog
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
EGFR Mouse anti-Human Monoclonal (pTyr1173) Antibody
Application:
WB, IP, ELISA
Reactivity:
Human, Mouse, Rat, Dog
Format:
Unconjugated, Unmodified
Specifications
Description
EGFR antibody LS-C6611 is an unconjugated mouse monoclonal antibody to EGFR (pTyr1173) from human. It is reactive with human, mouse, rat and other species. Validated for ELISA, IP and WB. Cited in 2 publications.
Target
Human EGFR
Synonyms
EGFR | EGF Receptor | ERBB | ERBB1 | MENA | PIG61 | Proto-oncogene c-ErbB-1 | V-erb-b homolog | EGF-R | HER1
Host
Mouse
Reactivity
Human, Mouse, Rat, Dog
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Gel filtration
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to aa 1170-1176 (N1170AEpYLRV1176) of EGFR (epidermal growth factor receptor) phosphorylated at Tyr1173.
Epitope
pTyr1173
Specificity
Recognizes the N1170AEpYLRV motif corresponding to the major autophosphorylation site of human EGF receptor. Does not cross-react with the non-phosphorylated human, mouse, rat and dog EGF receptor or with unrelated Tyr-phosphorylated proteins. Species cross-reactivity: mouse.
Applications
- Western blot (1 µg/ml)
- Immunoprecipitation (1 - 10 µg/10E6 cells)
- ELISA (0.05 µg/ml)
Usage
WB: For AP/BCIP/NBT (MTT) Detection:1 ug/ml. For HRPO/ECL deterction: 0.1 ug/ml. Use 0.5% Caseine, 0.5% BSA in PBST for blocking.
Presentation
PBS, 0.09% Sodium Azide, 40% Glycerol, Sucrose, PEG
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About EGFR
LSBio Ratings
EGFR Antibody (phospho-Tyr1173) for WB/Western, IP, ELISA LS-C6611 has an LSBio Rating of
Publications (4.1)
Learn more about The LSBio Ratings Algorithm
Publications (2)
Dasatinib and Doxorubicin Treatment of Sarcoma Initiating Cells: A Possible New Treatment Strategy. Aggerholm-Pedersen N, Demuth C, Safwat A, Meldgaard P, Kassem M, Sandahl Sorensen B. Stem cells international. 2016 2016:9601493. (WB; Human)
Increased PD-L1 expression in erlotinib-resistant NSCLC cells with MET gene amplification is reversed upon MET-TKI treatment. Christina Demuth, Morten Nørgaard Andersen, Kristine Raaby Jakobsen, Anne Tranberg Madsen, Boe Sandahl Sørensen. Oncotarget. 2017 September;8:68221-68229.
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat, Chicken
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Species:
Human, Mouse, Rat, Chicken
Applications:
IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Species:
Human
Applications:
Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
