Target
Human DGAT1
Synonyms
DGAT1 | ACAT-related gene product 1 | ACAT related gene product 1 | ARGP1 | ARAT | DGAT | Diglyceride acyltransferase | AGRP1
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
Biotin,
FITC.
Immunogen
Recombinant Human Diacylglycerol O-acyltransferase 1 protein (1-62AA)
Specificity
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.