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| Catalog Number | Size | Price |
|---|---|---|
| LS-C500206-50 | 50 µg | $294 |
| LS-C500206-100 | 100 µg | $360 |
Polyclonal Rabbit anti‑Human CYR61 Antibody (HRP) LS‑C500206
Polyclonal Rabbit anti‑Human CYR61 Antibody (HRP) LS‑C500206
Antibody:
CYR61 Rabbit anti-Human Polyclonal (HRP) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Horseradish Peroxidase, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CYR61 Rabbit anti-Human Polyclonal (HRP) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Horseradish Peroxidase, Unmodified
Other formats:
Specifications
Description
CYR61 antibody LS-C500206 is an HRP-conjugated rabbit polyclonal antibody to human CYR61. Validated for ELISA.
Target
Human CYR61
Synonyms
CYR61 | GIG1 | IGFBP10 | Protein CYR61 | CCN family member 1 | CCN1 | IBP-10 | IGF-binding protein 10 | IGFBP-10 | Protein GIG1
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Protein CYR61 protein (25-381AA)
Specificity
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
Applications
- ELISA
- Applications tested for the base form of this product only
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CYR61
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To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 2/12/2025
Date Requested: 2/12/2025
