Target
Human Complement C1R
Synonyms
C1R | Complement 1r | Complement C1R | Complement C1r subcomponent
Reactivity
Human
(tested or 100% immunogen sequence identity)
Purification
Immunoaffinity absorbed IgG
Specificity
Human Complement C1r. The reactivity of the antiserum is restricted to C1 r. In immunoelectrophoresis and radial immuno- diffusion (0uchterlony), using various antiserum concentrations against fresh normal human plasma a single precipitin line is obtained which shows a reaction of identity with the precipitin line obtained with purified C1r protein. Complexes containing C1q may also react with the antiserum. No reaction is obtained with C1 q, C1 s or any other plasma protein component or serum. Cross-reactivity The antiserum does not cross react with any other component of human plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail.