Human CLEC1A / CLEC-1

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Protein A purified

Unmodified

A recombinant protein fragment from the N-Terminus portion of human CLEC1.

N-Terminus

Human CLEC1A / CLEC-1.

• Western blot (2 - 5 µg/ml)

CLEC1 is a C-type lectin receptor and part of the [Character 91]Dectin-1 cluster' subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.

1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide

Store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q8NC01 NCBI: NM_016511 NP_057595.2