Human CELA3B / ELA3B

Mouse

Human (tested or 100% immunogen sequence identity)

IgG,k Monoclonal

ELTS3B-1

Unconjugated

Protein G purified

Unmodified. Also available Azide-free, BSA-free.

Partial recombinant protein (aa82-238).

aa82-238

Human CELA3B / ELA3B

• Western blot (1 - 2 µg/ml)
• ELISA (2 - 4 µg/ml)

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six genes which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein. it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. Optimal dilution of the CELA3B antibody should be determined by the researcher.

1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P08861 NCBI: NM_007352 NP_031378.1