Mouse CD68

Rabbit

Mouse, Rat (tested or 100% immunogen sequence identity)

Polyclonal

Unconjugated

Protein G purified

Unmodified

KLH-conjugated synthetic peptide from the N-Terminus of mouse CD68.

The CD68 antigen is involved in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 binds to tissue- and organ-specific lectins and selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane helps macrophages to move over selectin-bearing substrates and other cells. CD68 is highly expressed by blood monocytes and tissue macrophages as well as many tumor cell lines promoting binding to selectins on vascular endothelium facilitating dissemination to secondary sites.

• IHC (1:200 - 1:500)
• Immunofluorescence (1:100 - 1:500)
• Western blot (1:200 - 1:500)
• ELISA (1:500 - 1:1000)

PBS, pH 7.4, 0.09% Sodium Azide

Store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P34810 NCBI: NM_001251 NP_001242.2