Target
Human CD44
Synonyms
CD44 | CDW44 | CD44 antigen | Cell surface glycoprotein CD44 | CSPG8 | ECMR-III | Epican | HUTCH-I | LHR | MDU2 | MC56 | MIC4 | Hermes antigen | Hyaluronate receptor | Phagocytic glycoprotein 1 | PGP-1 | PGP-I | Pgp1 | Phagocytic glycoprotein I | MDU3 | CD44R | HCELL | Heparan sulfate proteoglycan
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Immunogen
Glutathione S Transferase (GST) fusion protein corresponding to the variable domains (v3 to v10) of human CD44.
Specificity
Recognizes an epitope encoded by exon v4 on the variant portion of human CD44. CD44v4 is strongly expressed on some breast cancer cell lines, notably epithelial-like BT-20 cells where v4 containing isoforms possess functional E-selectin ligand activity mediating cell adhesion under physiological flow conditions.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Presentation
TBS, 0.02% Sodium Azide, 1% BSA
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee