Human CD34

Rabbit

Human, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)

Bovine, Dog, Goat, Guinea pig, Horse, Sheep (at least 90% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

Synthetic peptide from the C-Terminus of human CD34 (QATSRNGHSARQHVVAD, aa366-382 of UniProt P28906). Percent identity by BLAST analysis: Human, Mouse, Rat, Ferret, Cat, Hamster, Dolphin, Elephant (100%); Sheep, Bovine, Goat, Horse, Guinea pig, Dog (94%); Bat, Pig (88%); Opossum (82%).

aa366-382

Human CD34

• IHC
• IHC - Paraffin (0.5 - 1 µg/ml)
• IHC - Frozen (0.5 - 1 µg/ml)
• Western blot (0.5 - 1 µg/ml)

CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 KD.CD34 is expressed in humans in hematopoietic stem cells, vascular endothelium, and blasts from 30% of patients with acute myeloid and lymphocytic leukemia. The human CD34 gene spans 26 kb and has 8 exons, a structure quite similar to that of the murine gene. By Southern blot analysis of DNA from a panel of human x mouse somatic cell hybrids using a CD34 cDNA probe demonstrate that the gene for CD34 is located on human chromosome 1 in the 1q12----qter region. CD34 plays an important role in the formation of progenitor cells during both embryonic and adult hematopoiesis.

Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.

Reconstitute in sterile distilled water.

Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P28906 NCBI: NM_001773 NP_001764.1