Target
Human CD28
Synonyms
CD28 | CD28 antigen | CD28 antigen (Tp44) | Tp44 | CD28 molecule
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated.
Also available conjugated with
APC,
Biotin,
FITC,
HRP,
PE.
Purification
Ion exchange chromatography
Immunogen
Human T lymphocytes
Specificity
Recognizes the 44kD antigen found on a sub-population of T-cells and activated B cells. These CD28+ CD8 cells are now known to be cytotoxic T-cell precursors. Does not react with B cells, granulocytes or monocytes. Species cross-reactivity: No cross-reactivity with canine tissues.
Applications
- Flow Cytometry
- Functional Assay
Usage
Suitable for use in Flow Cytometry, T cell proliferation and in cell stimulation studies where it has been suggested that measuring T cell function in HIV infected asymptomatic patients may be an early indicator of AIDS, independent of CD4+ cell counts.
Presentation
20 mM Tris, pH 8.0, 150 mM sodium chloride
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee