Target
Human CD28
Synonyms
CD28 | CD28 antigen | CD28 antigen (Tp44) | Tp44 | CD28 molecule
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
FITC.
Also available conjugated with
FITC,
Biotin,
APC,
PE, Cy5,
PE,
FITC,
Biotin,
PE,
FITC,
Biotin,
PE, Cy5,
Biotin,
FITC,
PE,
PE.
Purification
Ion exchange chromatography
Immunogen
Human peripheral blood T-cells.
Specificity
CD28 is a cell surface glycoprotein expressed by a subset of T lymphocytes. The antigen is a disulphide-linked homodimer of 44kD chains. CD28 is a ligand for the B cell marker CD80 (B7) and is important in the interaction of B and T cells during the immune response. It has been reported that this clone also recognizes an epitope of CD28 expressed by NK cells, which is not recognized by clones of 9.3 or CD28.2 (1.).