Human CD28

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1,k Monoclonal

C28/75

Unconjugated

Protein G purified

Azide-free, BSA-free. Also available Unmodified.

Recombinant human CD28 protein.

Human CD28

• Flow Cytometry (0.5 - 1 µg/10E6 cells)
• Functional Assay

This antibody recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. ELISA: Order BSA-free format for coating.

1X PBS

Store at -20°C or below. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P10747 NCBI: NM_006139 NP_006130.1