Human CD28

Mouse

Human, Mouse, Bovine, Pig, Sheep (tested or 100% immunogen sequence identity)

IgG2a,k Monoclonal

204-12

Unconjugated

Protein G purified

Unmodified. Also available Azide-free, BSA-free.

Stimulated human leukocytes were used as the immunogen for the CD28 antibody.

Human CD28

• Immunofluorescence (0.5 - 1 µg/ml)
• Flow Cytometry (0.5 - 1 µg/10E6 cells)

Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. Optimal dilution of the CD28 antibody should be determined by the researcher.

1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P10747 NCBI: NM_006139 NP_006130.1