Target
Human CD22
Synonyms
CD22 | CD22 molecule | CD22 antigen | SIGLEC2 | SIGLEC-2 | T-cell surface antigen Leu-14 | B-cell receptor CD22 | BL-CAM
Reactivity
Human, Monkey-Cynomolgus, Monkey-Rhesus
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Recombinant Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Immunogen
This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5-10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
Specificity
This antibody is specific for the 3rd Ig-like domain of human CD22 (epitope B), a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells.
Applications
- Immunoprecipitation
- Flow Cytometry
- Blocking
Usage
Applications should be user optimized.
Presentation
PBS, 0.02% ProClin™ 300.
Storage
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee