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| Catalog Number | Size | Price |
|---|---|---|
| LS-C44680-0.5 | 0.5 mg (1 mg/ml) | $671 |
Monoclonal Mouse anti‑Human CD209 / DC‑SIGN Antibody (clone MR‑1, Low Endotoxin, IF) LS‑C44680
Monoclonal Mouse anti‑Human CD209 / DC‑SIGN Antibody (clone MR‑1, Low Endotoxin, IF) LS‑C44680
Antibody:
CD209 / DC-SIGN Mouse anti-Human Monoclonal (Low Endotoxin) (MR-1) Antibody
Application:
IF, Flo
Reactivity:
Human
Format:
Unconjugated, Low Endotoxin
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CD209 / DC-SIGN Mouse anti-Human Monoclonal (Low Endotoxin) (MR-1) Antibody
Application:
IF, Flo
Reactivity:
Human
Format:
Unconjugated, Low Endotoxin
Other formats:
Specifications
Description
DC-SIGN antibody LS-C44680 is an unconjugated mouse monoclonal antibody to human DC-SIGN (CD209). Validated for Flow and IF.
Target
Human CD209 / DC-SIGN
Synonyms
CD209 | CD209 antigen | CD209 molecule | CDSIGN | CLEC4L | DC-SIGN | HIV gpl20-binding protein | DC-SIGN1
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
MR-1
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Low Endotoxin.
Also available Unmodified.
Immunogen
Immature myeloid monocyte-derived dendritic cells (MDDCs)
Specificity
Recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 that is also known as CD209. CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DCs in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DCs and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DCs. Clone MR-1 is reported to partially block the functional activity of DC-SIGN(2).
Applications
- Immunofluorescence
- Flow Cytometry
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Presentation
PBS
Storage
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CD209 / DC-SIGN
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC - Paraffin, Immunofluorescence, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 1/12/2025
Date Requested: 1/12/2025
