Target
Human CD121b / IL1R2
Synonyms
IL1R2 | CD121b | CD121b antigen | CDw121b | IL-1RT-2 | IL1R2c | Interleukin-1 receptor beta | Interleukin-1 receptor type II | IL-1R-beta | Antigen CDw121b | IL-1 type II receptor | IL-1R-2 | IL-1RT2 | IL1RB | Interleukin-1 receptor type 2
Reactivity
Human, Primate
(tested or 100% immunogen sequence identity)
Immunogen
This whole rabbit serum was prepared by repeated immunizations with recombinant human IL-1R type II.
Specificity
This antiserum is directed against the extracellular domain of the human IL-1R type II, but precipitates the intact receptor expressed on human cells. In general, this antibody also detects primate IL-1RII. The antibody does not recognize human IL-1, IL-1Ra or IL-1R type I. In ELISA formats and other immunoreactive assays, this antibody will detect the extracellular domain of the IL-1R type II (also called soluble IL-1R type II) found in human body fluids, particularly in the circulation, urine and supernatants of cells and synovial fluid.