Target
Human CCR5
Synonyms
CCR5 | C-C chemokine receptor 5 | CD195 antigen | CD195 | C-C CKR-5 | Chemokine c-c motif receptor 5 | Chemr13 | CMKBR5 | CKR5 | Cc chemokine receptor 5 | CCCKR5 | CCR-5 | Ccr5 receptor | Chemokine receptor CCR5 | HIV-1 fusion coreceptor | IDDM22 | C-C chemokine receptor type 5 | CC-CKR-5 | CKR-5
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
FITC,
Biotin.
Immunogen
Recombinant Human C-C chemokine receptor type 5 protein (302-352AA)
Specificity
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.