Target
Human CCR4
Synonyms
CCR4 | C-C chemokine receptor type 4 | CD194 | CD194 antigen | C-C CKR-4 | Chemr13 | CKR-4 | CC chemokine receptor 4 | CC-CKR-4 | CCR-4 | HGCN:14099 | C-c chemokine receptor 4 | Chemokine (C-C) receptor 4 | CKR4 | CMKBR4 | K5-5
Reactivity
Human
(tested or 100% immunogen sequence identity)
Immunogen
A synthetic peptide corresponding to a sequence of human CCR4 (LVELEVLQDCTFERYLDYAIQATETLAFVH).
Specificity
Predominantly expressed in the thymus, in peripheral blood leukocytes, including T-cells, mostly CD4+ cells, and basophils, and in platelets; at lower levels, in the spleen and in monocytes. Detected also in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expressing the cutaneous lymphocyte antigen (CLA). Expressed in brain microvascular and coronary artery endothelial cells.