Mouse CCL8 / MCP2

Rabbit

Mouse (tested or 100% immunogen sequence identity)

IgG Polyclonal

Biotin

Affinity purified

Unmodified

Recombinant mouse MCP-2.

Recognizes mouse MCP-2 (Monocyte Chemoattractant Protein 2), otherwise known as CCL8, a CC chemokine originally isolated from the human osteosarcoma cell line MG-63, which is expressed at highest levels in peripheral blood cells and the small intestine. MCP-2 acts as a chemoattractant for monocytes, lymphocytes, eosinophils and basophils, and signals through binding to the common MCP receptor, chemokine (C-C motif) receptor 2 (CCR2), and also CCR1 and CCR3. Proteolytic cleavage of MCP-2 into the NH2-terminally truncated form, MCP-2 (6-76), results in the loss of chemotactic activity, forming a functional CC chemokine inhibitor, which may be important during inflammatory responses.

• Western blot (0.1 - 0.2 µg/ml)
• ELISA (0.25 - 1 µg/ml)

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS

Reconstitute in sterile PBS.

Before reconstitution store at 4°C. After reconstitution store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P80075 NCBI: NM_005623 NP_005614.2