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order histories, retained contact details for faster checkout, review submissions, and special promotions.
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| Catalog Number | Size | Price |
|---|---|---|
| LS-C390916-20 | 20 µg (0.2 mg/ml) | $371 |
| LS-C390916-100 | 100 µg (0.2 mg/ml) | $574 |
1 of 2
2 of 2
Monoclonal Mouse anti‑Human BCL6 Antibody (clone SPM602, IHC) LS‑C390916
Monoclonal Mouse anti‑Human BCL6 Antibody (clone SPM602, IHC) LS‑C390916
Antibody:
BCL6 Mouse anti-Human Monoclonal (SPM602) Antibody
Application:
IHC-P
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
BCL6 Mouse anti-Human Monoclonal (SPM602) Antibody
Application:
IHC-P
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
BCL6 antibody LS-C390916 is an unconjugated mouse monoclonal antibody to BCL6 from human. It is reactive with human and mouse. Validated for IHC.
Target
Human BCL6
Synonyms
BCL6 | BCL6A | BCL-5 | BCL5 | Protein LAZ-3 | LAZ3 | ZBTB27 | ZNF51 | B-cell CLL/lymphoma 6 | B-cell lymphoma 5 protein | B-cell lymphoma 6 protein | BCL-6 | Zinc finger protein 51
Host
Mouse
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Clone
SPM602
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified.
Also available Azide-free, BSA-free.
Immunogen
Recombinant human protein.
Specificity
Human BCL6
Applications
- IHC - Paraffin (0.13 - 0.25 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large (L&H) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma. Optimal dilution of the anti-Bcl6 antibody should be determined by the researcher. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BCL6
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Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC - Paraffin
Species:
Human, Mouse
Applications:
IHC - Paraffin
Species:
Human
Applications:
IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/15/2024
Date Requested: 11/15/2024
