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| Catalog Number | Size | Price |
|---|---|---|
| LS-C498425-50 | 50 µg | $294 |
| LS-C498425-100 | 100 µg | $360 |
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Polyclonal Rabbit anti‑Human APG4B / ATG4B Antibody (IHC, IF, WB) LS‑C498425
Polyclonal Rabbit anti‑Human APG4B / ATG4B Antibody (IHC, IF, WB) LS‑C498425
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
ATG4B antibody LS-C498425 is an unconjugated rabbit polyclonal antibody to ATG4B (APG4B) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
Target
Human APG4B / ATG4B
Synonyms
ATG4B | APG4 autophagy 4 homolog B | AUTL1 | Autophagin-1 | Cysteine protease ATG4B | HAPG4B | APG4B | KIAA0943
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Cysteine protease ATG4B protein (350-400AA)
Specificity
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Applications
- IHC
- Immunofluorescence
- Western blot
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About APG4B / ATG4B
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Featured Products
Species:
Human, Mouse, Rat, Chicken, Xenopus, Pufferfish, Zebrafish
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse
Applications:
Western blot, Immunoprecipitation
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
